Stress protein responses in rat brain of PB-withdrawal syndrome

The role of spinal serotonergic system in morphine withdrawal syndrome in the rat

Previous pharmacological studies have implicated serotonergic brain systems in opiate withdrawal syndrome. Increased brain 5-HT release is associated with the development of physical dependence to morphine. Specific serotonin reuptake inhibitors, such as fluvoxamine and sertraline reduce the severity of naloxone precipitated opioid withdrawal syndrome. Other studies have shown that 5-HT system ...

The role of spinal serotonergic system in morphine withdrawal syndrome in the rat

Previous pharmacological studies have implicated serotonergic brain systems in opiate withdrawal syndrome. Increased brain 5-HT release is associated with the development of physical dependence to morphine. Specific serotonin reuptake inhibitors, such as fluvoxamine and sertraline reduce the severity of naloxone precipitated opioid withdrawal syndrome. Other studies have shown that 5-HT system ...

P48: Protein Changes Resulted in Sub-Chronic Neurotoxicity of Bisphenol A in Rat Brain

Bisphenol A (BPA) is one of the most widely used chemicals in the plastic industry, which enter the human body through occupational and food contact. In this study, the protein changes in rat cerebral cortex was evaluate in order to evaluate the neurotoxicity of BPA. 24 adult male rats were randomly selected and divided into four groups (n=6) and each group respectively received 0, 0.5, 5 and 5...

Effects of psychotropic drugs on nerve growth factor protein levels in the rat brain

Introduction: Psychotropic drugs exert their effects, in part, by increasing neurotrophin levels in the brain. Nerve growth factor (NGF) protein levels after treatment with only a limited number of psychotropics have been determined. The present study was designed in order to evaluate the effects of acute and chronic administration of different psychotropic drugs on NGF protein levels in fiv...

carbenoxolone attenuated morphine-induced withdrawal syndrome in rat